Salivary duct carcinoma is a rare, typically highgrade malignant epithelial neoplasm composed of structures that resemble expanded salivary gland ducts. A low-grade variant exists. Incidence rates vary depending upon the study cited. In the AFIP files, salivary duct carcinomas represent only 0.2 per cent of all epithelial salivary gland neoplasms. More than 85 per […]

Oncocytic carcinoma is a rare, predominantly oncocytic neoplasm whose malignant nature is reflected both by its abnormal morphologic features and infiltrative growth. Bauer and Bauer reported the first case in 1953. Although focal oncocytic features are seen in a wide variety of salivary neoplasms, both benign and malignant oncocytic neoplasms are extremely rare. Clinical Features.

Mucinous adenocarcinoma is a rare malignant neoplasm characterized by large amount of extracellular epithelial mucin that contains cords, nests, and solitary epithelial cells. The incidence is unknown. Limited data indicate that most, if not all, occur in the major salivary glands with the submandibular gland as the predominant site. These tumors may be associated with

Cystadenocarcinoma is the malignant counterpart of cystadenoma. It is a rare malignant epithelial tumor characterized histologically by prominent cystic and, frequently, papillary growth but lacking features that characterize cystic variants of several more common salivary gland neoplasms. Clinical Features. Cystadenocarcinoma is considered to be a low-grade neoplasm. Most of the cases, about 65 per cent,

Basa cell adenocarcinoma of salivary glands is an uncommon and recently described entity occurring almost exclusively at the major salivary glands. It is a low grade malignant neoplasm that is cytologically similar to basal cell adenoma, but is infiltrative and has a small potential for metastasis. Clinical Features. In AFIP case files spanning almost 11

Epithelial-myoepithelial carcinoma is an uncommon, biphasic low-grade epithelial neoplasm composed of variable proportions of ductal and large, clear-staining, differentiated myoepithelial cells. It comprises approximately 1 per cent of all epithelial salivary gland neoplasms. Clinical Features. This is predominantly a tumor of the parotid gland. In the AFIP case files, the mean age of patients is

Polymorphous low-grade adenocarcinoma (PLGA) is a malignant epithelial tumor that is essentially limited in occurrence to minor salivary gland sites and is characterized by bland, uniform nuclear features; diverse but characteristic architecture; infiltrative growth; and perineural infiltration. This is a recently recognized type of salivary gland tumor first described in 1983. Evans and Batsakis first

  Adenoid cystic carcinoma (formerly known as ‘cylindroma’) is a slow-growing but aggressive neoplasm with a remarkable capacity for recurrence, It is characterized by proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid and cystic patterns. In a review of its case files, the AFIP found adenoid cystic carcinoma to be the fifth

Mucoepidermoid carcinoma is a malignant epithelial tumor, first studied and described as a separate entity by Stewart, Foote and Becker in 1945. As the name implies, the tumor is composed of both mucus-secreting cells and epidermoid-type cells in varying proportions. Columnar and clear cells are also seen, and often demonstrate prominent cystic growth. It is

Most salivary gland tumors arise from the epithelium of the duct apparatus, but occasionally lesions seem to show acinar cell differentiation. Acinic cell carcinoma is a malignant epithelial neoplasm in which the neoplastic cells express acinar differentiation. Some authors advocate the existence of both benign and malignant acinic cell neoplasms, whereas others are of the